The current testing rate for BRCA 1/2 mutations is currently 68% in HER2-negative early breast cancer, but eligible patients could receive better care if tested. The current rate of BRCA1/2 testing ...

In this analysis, researchers explored patterns of surgical care and factors associated with undergoing bilateral mastectomy as primary breast surgery.

Using current treatment costs and medical guidelines, genetic testing for BRCA1/2 mutations among apparently healthy women at high risk of breast and/or ovarian cancer was deemed cost-effective in a ...

In late December of 2013, the US Preventive Services Task Force (USPSTF) provided an update to its 2005 recommendations, reaffirming the genetic risk assessment and breast cancer susceptibility gene ...

Lifetime cancer risk is modified by family history in women who undergo BRCA1 or BRCA2 testing, according to a study.

Harmful variants in the BRCA1 gene greatly increase a person's lifetime risk of developing breast, ovarian and pancreatic cancers, but most people are unaware they are carriers. In a new study in the ...

Researchers have understood for decades the importance that DNA repair mechanisms play in maintaining genomic integrity and keeping carcinogenesis in check. For instance, the BRACA1/2 genes and ...

Harmful variants in the BRCA1 gene greatly increase a person's lifetime risk of developing breast, ovarian and pancreatic cancers, but most people are unaware they are carriers. "Many patients will ...

BRCA testing helps determine if you have a gene mutation that increases your cancer risk. People with a family history of certain cancers may consider BRCA testing. A positive BRCA result does not ...

Women who test negative for BRCA gene mutations may still be at greater risk of developing breast cancer than the general population, according to a study led by Cedars-Sinai Health Sciences ...

Not only do home genetic test kits, like 23andMe, provide information about your ancestry, but they can also give you some insights into your inherited health risks, particularly mutations on the BRCA ...

Testing for BRCA mutations is an important step in developing the treatment plan for patients with breast cancer, says Leslie Randall. For patients with ovarian cancer, early identification of BRCA ...