In a study published in Nature Aging on Nov. 26, a research team from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences revealed that aging specifically impairs ...

In a recent study published in Nature Methods, researchers developed "scAtlasVAE," a deep-learning model to integrate large-scale single-cell ribonucleic acid (RNA) sequencing (scRNA-seq) data, ...

IL-2 is clinically validated as an immunotherapeutic, but its use is limited by toxicity issues. AZD-6750 is an approach from Astrazeneca plc that applies cis-guiding to deliver a modified IL-2 mutein ...

Antigen-driven TCR signaling in the epidermis during CD8+ TRM differentiation results in a lower TGFβ requirement for persistence and increased proliferative capacity that together enhance epidermal ...

One of the ways scientists are trying to improve cancer treatments is by better equipping the body's own immune system to ...

As the trained killers of the immune system, cytotoxic T cells silently save our lives every day—vanquishing viruses before they can run amok, and putting nascent cancer cells out of business before ...

New findings could aid future development of more efficient therapeutic strategies in the context of regenerative medicine and aging.

Lymphatic malformations (LMs) are congenital vascular anomalies characterized by abnormal lymphatic development, leading to ...