Human-induced pluripotent stem cell-derived cardiomyocyte sheets can be a life-saving intervention for patients with advanced cardiovascular disease. Administration of immunosuppressive agents to ...

The problem is that mammalian heart muscle cells, known as cardiomyocytes, lose their ability to proliferate shortly after birth. Researchers have long sought to induce these cells to start dividing ...

Announcing a new publication for Acta Materia Medica journal. Heart failure (HF) remains a major global health challenge with ...

The induction of the cell cycle in cardiomyocytes involves the activation of specific genes that are responsible for regulating cell division and growth. Our laboratory has discovered several ...

Reintroduction of the Cyclin A2 gene enables adult human cardiomyocytes to divide, producing functional daughter cells and promoting heart repair. The therapy uses a replication-deficient adenoviral ...

“For decades, researchers have been trying to find the specialized cells that make new muscle cells in the adult heart, and we think that we have found that cell,” Hesham Sadek, the senior author of ...

In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem cells, or hiPSCs, that ...

Prevalence and temporal trends of prostate cancer among patients with acute cardiovascular diseases in the United States: A National Inpatient Sample analysis.

Dlc1 deletion affects cardiac differentiation in mouse embryonic stem cells by activating the canonical Wnt pathway ...

Severe heart attacks often progress to end-stage heart failure because the dearth of heart muscle cells diminishes pumping power of the heart’s left ventricle. The damaged heart, unable to repair ...