As the executioners of apoptosis, caspases are a cellular sword of Damocles, lurking inside almost every metazoan cell, poised to kill it in response to intrinsic or extrinsic signals. The literature ...

There is scarcely a form of life – whether it be viral, microbial, plant or animal, that does not encode at least one protease. Indeed, because the ability to recycle scarce amino acids in early ...