Medscape

Estimating Glomerular Filtration Rate with a Modification of Diet in Renal Disease Equation: Implications for Pharmacy

Cockcroft–Gault, using TBW (mL/min) TBW(140 – age)/(72 x SCr) 75. . . Cockcroft–Gault, using IBW (mL/min) IBW(140 – age)/(72 x SCr) 50. . . Cockcroft–Gault ...
Nature

Comparing the Cockcroft–Gault and MDRD equations for calculation of GFR and drug doses in the elderly

Both the Cockcroft–Gault and the Modification of Diet in Renal Disease (MDRD) equations are used to guide adjustment of medication dose according to renal function. Neither equation has been validated ...
Medscape

Estimating Aminoglycoside Clearance and Creatinine Clearance in Underweight Patients

Am J Health Syst Pharm. 2010;67(4):274-279. The objectives of this study were to develop and test an adjustment factor (AF) for estimating aminoglycoside clearance (CL amino) from the Cockcroft–Gault ...
ascopubs.org

Assessment of the impact of the chemotherapeutic regimen on the Cockroft-Gault formulae in estimating renal function in elderly cancer patients.

Weight loss: An important but often overlooked clue for the diagnosis of cancer. Background: More and more elderly cancer patients are treated with cytotoxic agents. Elderly patients represent an ...
Healio

Drug dosing and new measures of serum creatinine: Clear as mud

Please provide your email address to receive an email when new articles are posted on . Appropriate drug dosing requires an estimation of kidney function that is reliable and consistent across many ...
ascopubs.org

The accuracy of carboplatin area under the curve (AUC) estimated by Calvert formula using Cockcroft-Gault formula and Thai eGFR in Thai cancer patients.

ARGX-111 shows activity in MET-amplified patients in a phase-I study and in preclinical models of myeloid-derived suppressor cell (MDSC) depletion in the tumor microenvironment. This is an ASCO ...
Pulse

Researchers warn against using eGFR to check renal function when prescribing newer oral anticoagulants

UK researchers are urging a switch to the Cockroft-Gault equation to estimate renal function in patients prescribed the newer oral anticoagulants. They say use of the MDRD calculator – currently used ...