Steroidogenesis-mediated production of neurosteroids is important for brain homeostasis. Cytochrome P450 17A1 (CYP17A1), which converts pregnenolone to dehydroepiandrosterone (DHEA) in endocrine ...
We recently reported increased adrenal cortisol responses to intravenously administered adrenocorticotropic hormone (ACTH) 1−24 in premenopausal women with chronic post-traumatic stress disorder (PTSD ...
Physiological replacement dosages of oral DHEA in healthy people older than 40 years are in the range of 20-50 mg/day for men and 10-30 mg/ day for women. [2,4,8] These dosages are usually adequate to ...
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