Cells use RNA as a versatile tool to regulate the activity of their genes. Small snippets of RNA can fine-tune how much protein is produced from various genes; some small RNAs can shut genes off ...

(SALT LAKE CITY)—Dicer, an enzyme essential for life, cleaves long double-stranded RNA (dsRNA) into short pieces that regulate gene expression. But in many ways dsRNA molecules all look alike, and ...

Ten years ago, researchers obtained the first crystal structure of Dicer, a key enzyme in a biological process called RNA interference (RNAi). In RNAi, a process also known as gene silencing, a short ...

Cells use RNA as a versatile tool to regulate the activity of their genes. Small snippets of RNA can fine-tune how much protein is produced from various genes; some small RNAs can shut genes off ...

WATERTOWN, Mass.--(BUSINESS WIRE)--Dicerna Pharmaceuticals, Inc., an emerging pharmaceutical company developing RNA interference (RNAi)-based therapeutics against genetically-defined targets in ...

How an enzyme, appropriately named DICER, cuts double-stranded RNA to produce short sections of RNA that regulate genes has been revealed. Small snippets of RNAs can turn off genes, stopping them from ...

Recent work pinpoints critical changes in an enzyme known as DICER, which create a cascade of effects on this microRNAome. The team identified primary actors circ2082, a circular RNA, and RBM3, an RNA ...

New insights into the function of Dicer and miRNAs in mouse development... The RNase III Dicer enzyme processes RNAs into small interfering (si)RNAs and micro (mi)RNAs. Previous studies in several ...

The discovery of a novel cellular “switch” in the popular laboratory research worm, C. elegans, by a University of Colorado at Boulder team may provide researchers with a new means of triggering ...

A research team led by the University of Colorado at Boulder has discovered a previously unknown cellular "switch" that may provide researchers with a new means of triggering programmed cell death, ...