When it comes to detecting rare cancer-causing mutations, both sensitivity and specificity matter. In the past few years, digital PCR (dPCR) has captured the attention of researchers and clinicians ...

Digital PCR (dPCR) is a rediscovered method that researchers use for the absolute quantification of nucleic acid samples. Compared to quantitative real-time PCR, dPCR is more sensitive, precise, and ...

Leukemia is an umbrella term for multiple different cancers that form in the blood, one such member of the leukemia family being chronic myelogenous leukemia (CML). CML is caused by a chromosomal ...

an immersive virtual event dedicated to exploring the remarkable capabilities of digital PCR. This experience invites you to delve into the forefront of scientific innovation across diverse research ...

Gene therapy (introducing genetic material into living cells to fix, replace, enhance, or block a faulty gene) is rapidly gaining traction as a strategy for the treatment of genetic diseases. The ...

The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.

Scientists manufacture many biotherapeutic products in immortalized cell lines, most commonly HEK293. Residual HEK293 DNA in biotherapeutic candidates can harbor tumorigenic or retroviral sequences ...

A team of UK-based scientists has recently developed an allele-specific probe polymerase chain reaction method that can accurately detect different variants/lineages of severe acute respiratory ...

PCR is a technique used to amplify target DNA in a sample. It’s a well-known method that has undergone numerous modifications to enhance its capabilities. This year, it’s turning 40 years old. PCR has ...