Direct evidence that microtubules function as mechano-sensors and regulate the intracellular transport of molecules has been reported, leading to new possibilities in the fields of biomechanics, ...

Constructed with tubulin heterodimers connected into a hollow cylinder, the microtubule, an essential component of the cytoskeleton, plays a vital role in various intracellular processes. In a recent ...

Microtubules are involved in various functions, which are mediated by complex interactions with a large range of microtubule-interacting proteins, such as motor proteins, microtubule stabilizers and ...

Microtubules are active protein polymers critical to the structure and function of cells and the process of cell division. In a living cell their growing ends constantly elongate and retreat in a ...

Microtubules are cell constituents that display several astounding properties and a unique pattern of behavior during the cell cycle. Microtubules are regulated by several proteins and complexes, and ...

When a cell divides, it performs a feat of microscopic choreography—duplicating its DNA and depositing it into two new cells. The spindle is the machinery behind that process: It latches onto ...

A new study by researchers from Drexel University College of Medicine reverses the popular scientific dogma that the protein tau stabilizes microtubules within brain cells. The scientists’ new ...

Microtubules function in concert with associated proteins that modify microtubule behavior and/or transmit signals that effect changes in growth. To better understand how microtubules and their ...

Direct evidence that microtubules function as mechano-sensors and regulate the intracellular transport of molecules has been reported, leading to new possibilities in the fields of biomechanics, ...