Precursor cells in the embryonic neural tube are organized in a specific striped pattern which depends on the signals they receive (left). Lehr and colleagues recreated this pattern in a cell culture ...

The study revealed the small-molecule signaling system for mammalian cell-cell communication that combines super-sensitivity with a chassis-friendly, low-burden design, and demonstrated the system's ...

Drosophila wing development is a paradigm for understanding how spatial information is conveyed by morphogen gradients to coordinate pattern formation and organ growth. Central to this process is ...

Discover the first images of cytonemes during mammalian neural development, serving as express routes to establish morphogen gradients and tissue patterning. St. Jude Children's Research Hospital ...

In a recent study published in Nature Communications, researchers examinea the effects of temporal morphogen gradient during neural induction (NI) on the formation of brain organoids. Study: Temporal ...