Researchers from Children's Hospital of Philadelphia (CHOP) have developed a method to help cancer immunotherapies reach ...

Neuroblastoma cells. The oncogene MYCN is stained turquoise. Cell nuclei are marked in blue. Pink signals a change in chromatin, which is characteristic of dormant cells. Cells with few copies of the ...

Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. Scientists resolved the mystery, showing the drug 'hijacks' a normal ...

A groundbreaking study led by Children's Hospital Los Angeles has found a novel mechanism behind neuroblastoma progression: the shape and structure of the extracellular matrix. The study, led by ...

Neuroblastoma is the most common childhood tumor occurring outside the brain. Until now, studying genetic changes and their role in neuroblastoma initiation has been challenging due to the lack of ...

Neuroblastoma is a cancer that affects the sympathetic nervous system of children. It is unusual among cancers because it shows a range of outcomes: from aggressive, potentially fatal progression to a ...

PHILADELPHIA, April 14, 2025 /PRNewswire/ -- Researchers at Children's Hospital of Philadelphia (CHOP) developed a longitudinal atlas of neuroblastoma, a common and potentially deadly childhood cancer ...