The contractile responses of esophageal smooth muscle (SM) induced by platelet-activating factor (PAF) involve the activation of L-type voltage-dependent calcium channels (L-type VDCCs), ...
PAF causes strong contractions—especially in the muscles of the esophagus and the stomach’s upper region (called the gastric fundus). In other parts of the intestine, such as the small intestine and ...
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Compound found in rice bran can suppress intestinal contractions by inhibiting calcium influx
A research team at Toho University has revealed that ferulic acid (FA), a polyphenol abundant in rice bran, suppresses intestinal smooth muscle contractions by inhibiting voltage-dependent calcium ...
Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in 8,000 people. While it is well known for causing muscle weakness and stiffness, DM1 also ...
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Scientists reveal how a key inflammatory molecule triggers esophageal muscle contraction
A research group has uncovered important details about how platelet-activating factor (PAF)—a powerful molecule involved in inflammation and allergic reactions—triggers contractions in the smooth ...
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