A team of researchers from the University at Buffalo in Amherst, NY have successfully engineered a novel variant of streptavidin that forms a stable monomer and is capable of monovalent biotin ...

A team of researchers from the University at Buffalo in Amherst, NY have successfully engineered a novel variant of streptavidin that forms a stable monomer and is capable of monovalent biotin ...

Recent research by Rafael C. Bernardi at the University of Illinois, Urbana-Champaign examines why a common tool in biotechnology -- the binding of streptavidin to biotin -- shows different mechanical ...

Reengineered streptavidin mutants bind biotin-4-fluorescein with extremely tight yet reversible binding affinity. The terrifically tight noncovalent interaction between biotin and streptavidin has ...

Biotin can amplify signals by forming complexes of large size with avidin or streptavidin. There are several techniques that use biotinylated secondary antibodies for this purpose, which are dealt ...

The interaction between biotin and streptavidin is a well-established experimental tool in bionanotechnology. Physicists have now shown that the mechanical stability of the complex is dependent on the ...

Please provide your email address to receive an email when new articles are posted on . An excess of biotin can result in false-negative allergen-specific IgE results during the one-step ...

Pretargeted radioimmunotherapy (PRIT) combines antibody-mediated immunotherapy with targeted delivery of radioisotopes. It is a multi-step process, first the administration of a monoclonal antibody, ...

The Sheldon Park Laboratory uses knowledge of protein structure-function relationship to engineer improved or novel protein molecules, for use in biotechnology and therapy. Researchers use a rational ...