A handful of agonist peptide–MHC complexes can evoke a sustained signal from the T cell receptor. A combination of mathematical models and imaging experiments suggests a key function for CD4 and ...
This is a preview. Log in through your library . Abstract Src family kinase Lck plays critical roles during T cell development and activation, as it phosphorylates the TCR/CD3 complex to initiate TCR ...
Improving CAR-T cell therapy for solid tumours through inhibition of conventional signalling pathway
National University of Singapore, Yong Loo Lin School of Medicine Chimeric Antigen Receptor-expressing T cell (CAR-T) therapy involves re-engineering specific immune cells called T cells to target ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback