Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...

AGGREGATION of platelets in the presence of adenosine diphosphate (ADP) appears to be important in hæmostasis and in the genesis of platelet thrombosis. There is evidence that this reaction is common ...

Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...

Researchers at Gifu University’s Institute for Glyco-core Research have developed two synthetic approaches to produce a fragment of a molecule called poly(ADP-ribose). By developing two ways to ...

In a recent study posted to the bioRxiv* preprint server, researchers discovered compounds able to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) macrodomain 1 (Mac1) and ...

A small cut won’t bleed for long because tiny blood cells called platelets stick together and trigger clots. Damaged blood vessels and red blood cells release a compound known as adenosine diphosphate ...

Pseudomonas aeruginosa exoenzyme S is an adenosine diphosphate ribosyltransferase distinct from Pseudomonas toxin A. Exoenzyme S catalyzes the transfer of radioactivity from all portions of ...

Adenosine is a nucleoside that occurs naturally in all cells of the body. Chemically it is 6-amino-9-beta-D-ribofuranosyl-9-H-purine. Adenosine is made up of adenine attached to a ribose sugar ...

The ultimate goal for vaccination is to stimulate protective immunological memory. Protection against infectious diseases not only relies on the magnitude of the humoral immune response, but more ...