Pathogen adaptation occurs when novel variants gain greater fitness in the current environment than their predecessors. Host immunity, whether vaccination- or infection-induced, could shape the ...

Heterogeneity is ubiquitous in real-world host populations, yet most theories assume homogeneity. Using a metapopulation model, we examine how host heterogeneities, such as uneven movement patterns ...

A parasite which has devastating impacts on agriculture and human health is the first pathogen to have its proteins located and mapped within its cells -- providing clues to their function and helping ...

The evolution of pathogens has received attention in a wide range of scientific fields, such as epidemiology, demography, and evolutionary ecology. Understanding pathogen evolution is particularly ...

Evolution of bacterial pathogen populations has been detected in a variety of ways including phenotypic tests, such as metabolic activity, reaction to antisera and drug resistance and genotypic tests ...

Combining genomic data and human travel patterns over a 14-year period in South Africa reveals key insights into the spread, evolution and resistance patterns of a major bacterium behind pneumonia and ...

The rapid identification and genomic analysis of zoonotic pathogens are critical for safeguarding public health and controlling outbreaks. PathoBase, an advanced computational platform, provides a ...

As long as humans have been around, there have been pathogens to make us sick. Some have achieved infamy in human history—the bubonic plague, for example, or smallpox—and with modern technologies, ...

A committee-supported project or activity that has been completed and for which output dissemination has begun. Its committee has been disbanded and closeout procedures are underway. A planning ...

A chance discovery in a Vermont cheese cave has given scientists a rare glimpse of evolution unfolding in real time – and the unexpected findings have broad implications for protecting human health, ...