Chromogenic in situ hybridization - Wikipedia
[1] CISH probes are approximately 20 nucleotides in length and are designed for DNA targets. They are complementary to the targeted sequence and bind to it after a denaturation and hybridization step.
What is Chromogenic In Situ Hybridization (CISH)?
Jul 29, 2025 · What is Chromogenic In Situ Hybridization (CISH)? Chromogenic In Situ Hybridization (CISH) is a molecular technique used to visualize specific DNA or RNA sequences directly within …
In Situ Hybridization (ISH), CISH, and FISH Reagents | Thermo ...
There are two basic ways to visualize your RNA and DNA targets in situ —fluorescence (FISH) and chromogenic (CISH) detection. Characteristics inherent in each method of detection (see table …
CISH Gene - GeneCards | CISH Protein | CISH Antibody
Nov 13, 2025 · Complete information for CISH gene (Protein Coding), Cytokine Inducible SH2 Containing Protein, including: function, proteins, disorders, pathways, orthologs, and expression.
CISH impairs lysosomal function in activated T cells ... - Nature
Apr 17, 2023 · Here we show that activated T cells from older adults contribute to inflammaging by releasing mitochondrial DNA (mtDNA) into their environment due to an increased expression of the...
Targeting the intracellular immune checkpoint CISH with ...
Apr 29, 2025 · The complete response of colorectal cancer in a patient whose malignancy was previously refractory to conventional immuno-oncologic agents presents a new potential treatment …
The most compelling evidence supporting the therapeutic potential of targeting CISH comes from 243 the first-in-human clinical trial employing CRISPR-mediated knockout of CISH in T cells administered …