Sep 9, 2024 · Diagnosis of CM relies on the presence of typical skin lesions, a positive Darier's sign (where mechanical rubbing of lesions causes oedema and erythema), and/or histology showing mast …

This is known as Darier's sign and is a diagnostic feature of mastocytosis (Hogan & Lewis, 2002; Kuznar, 1998; Leaf, Jaecks, & Rodriquez, 1996).

Aug 23, 2011 · Medscape Dermatology Clinic Cutaneous Eruption in Childhood: What Does This Teen Have? This young man is covered with papules that exhibit a positive Darier sign.

Cutaneous Eruption in Childhood: What Does This Teen Have? This young man is covered with papules that exhibit a positive Darier sign. Medscape Dermatology, August 16, 2012

May 24, 2001 · Darier's disease, or keratosis follicularis, is a rare inherited autosomal dominant disease affecting the skin, nails, and mucosa. Gene mutation at a single locus on chromosome 12q23-q24.1 …

An Ominous Sign: Fetal Ascites at Mid-gestation The differential diagnosis of fetal ascites with pleural effusion is broad. Can you figure out the cause of these ultrasonographic findings?

An Ominous Sign: Fetal Ascites at Mid-gestation The differential diagnosis of fetal ascites with pleural effusion is broad. Can you figure out the cause of these ultrasonographic findings?

Cutaneous Eruption in Childhood: What Does This Teen Have? This young man is covered with papules that exhibit a positive Darier sign. Medscape Dermatology, August 16, 2012 Previous Next

Dec 3, 2025 · Low daily step counts predict Parkinson's disease years before diagnosis but are likely a sign of early disease, not a risk factor.

Aug 16, 2012 · The Darier sign is usually negative in patients with TMEP because the lesions are paucicellular, and insufficient mast cells are present for significant degranulation to occur.