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  1. Factor V Leiden Mutation - StatPearls - NCBI Bookshelf

    Apr 8, 2023 · Factor V Leiden is a point mutation of factor V, resulting in an elimination of the cleavage site in factor V and factor Va. This genetic defect leads to an increased risk of thrombosis, especially …

  2. Factor V Leiden - Symptoms and causes - Mayo Clinic

    Aug 23, 2022 · Factor V Leiden (FAK-tur five LIDE-n) is a mutation of one of the clotting factors in the blood. This mutation can increase your chance of developing abnormal blood clots, most commonly …

  3. Factor V Leiden: Symptoms & Treatment - Cleveland Clinic

    Factor V deficiency is a rare bleeding disorder that affects about 1 in 1,000,000 people. It can involve recurrent nosebleeds, heavy menstrual bleeding and prolonged bleeding after surgery.

  4. Factor V Leiden - Wikipedia

    Factor V Leiden (rs6025 or F5 p.R506Q[1]) is a variant (mutated form) of human factor V (one of several substances that helps blood clot), which causes an increase in blood clotting (hypercoagulability).

  5. Factor V Leiden Thrombophilia: Causes, Symptoms & Treatment

    Aug 15, 2025 · Factor V Leiden thrombophilia is a genetic condition caused by a mutation in the F5 gene that results in a defective Factor V protein, making it resistant to inactivation by activated protein C …

  6. Factor V Leiden: Symptoms, Cause, Diagnosis, and Treatment

    Oct 13, 2024 · Factor V Leiden makes it harder for your clots to break up. If the clots don't go away, you're more likely to have them in the veins in your legs. This is called deep vein thrombosis (DVT).

  7. Factor V Leiden Thrombophilia - GeneReviews® - NCBI Bookshelf

    May 14, 1999 · Factor V Leiden thrombophilia is characterized by venous thromboembolism (VTE) manifesting most commonly in adults as deep vein thrombosis (DVT) in the legs or pulmonary …

  8. Factor V deficiency: MedlinePlus Genetics

    Factor V deficiency is a rare bleeding disorder. The signs and symptoms of this condition can begin at any age, although the most severe cases are apparent in childhood.

  9. Factor V Test: Meaning, Low & High Levels, Symptoms, and Uses

    Learn about the Factor V test: what it measures, causes of low or high levels, symptoms, sample type, and its role in diagnosing bleeding and clotting disorders.

  10. Factor V Leiden thrombophilia: MedlinePlus Genetics

    Factor V Leiden thrombophilia is an inherited disorder of blood clotting. Factor V Leiden is the name of a specific gene mutation that results in thrombophilia, which is an increased tendency to form …