Lambda Exonuclease is a processive enzyme that catalyzes 5' to 3' mononucleotide removal from dsDNA with a preferred substrate of a 5' phosphate.

Description Lambda Exonuclease is a highly processive 5'→3' exodeoxyribonuclease. It selectively digests the 5’-phosphorylated strand of double-stranded DNA. The enzyme exhibits …

Principle The protein is produced by a strain of E. coli that overexpresses the exonuclease gene from bacteriophage Lambda. One unit is defined as the amount of enzyme required to produce …

Jul 23, 2025 · Lambda exonuclease is an enzyme derived from bacteriophage lambda, a virus that infects Escherichia coli bacteria. It functions as a nuclease, specifically degrading DNA.

Sep 18, 2024 · Using single-molecule fluorescence resonance energy transfer analysis, we discover the enzymatic activity of bacteriophage λ exonuclease (λExo).

λ Exonuclease is a highly processive 5′→3′ exonuclease that degrades double-stranded (ds)DNA. The single-stranded DNA produced by λ exonuclease is utilized by homologous pairing …

Thermo Scientific Lambda Exonuclease is a highly processive 5'→3' exodeoxyribonuclease. It selectively digests the 5'-phosphorylated strand of double-stranded DNA.

Jul 24, 2019 · Lambda Exonuclease efficiently degrades 5' phosphorylated linear dsDNA from 5' to 3' direction, leaving supercoiled dsDNA intact

Aug 1, 1999 · Here, we have begun by examining the substrate preferences of lambda exonuclease and its interaction with DNA using short defined oligodeoxy-ribonucleotides.

NS-seq depends on the ability of lambda exonuclease (λ-exo) to efficiently digest parental DNA while leaving RNA-primer protected nascent strands intact. We used genomics and …