Compounds containing 2 geminal phosphonate groups are known as bisphosphonates. They were first synthesized in 1897 by Von Baeyer and Hofmann and now form the basis for an important class of …

Nov 10, 2025 · The defining feature of a phosphonate compound is the direct, covalent carbon-phosphorus (C-P) bond. This structure distinguishes phosphonates from inorganic phosphates, …

Phosphonates (or phosphonic acids) are a broad family of organic molecules based on phosphorus (chemical symbol P), carbon (C), oxygen (O) and hydrogen (H). A variety of phosphonates (including …

Oct 1, 2025 · What's In A Name? In the broadest sense, the term phosphonate describes any compound containing a carbon to phosphorus bond. Some examples of phosphonate compounds include …

Jul 26, 2025 · Rare but serious side effects, such as osteonecrosis of the jaw or atypical femur fractures, have been observed with long-term use, prompting specific clinical guidelines for patient …

Jun 27, 2019 · Ciliatine (compound 1) is the most ubiquitous phosphonate present in lower organisms and occurs in remarkably high amounts. It is either presented in a free, unbound form being a …

May 21, 2024 · Occasionally called phosphites, a phosphonate is a salt or an ester of one of a family of phosphonic acids. The simplest — unsubstituted — phosphonic acid is H- (PO)- (OH) 2, a crystalline …

Compounds with a phosphonate group, i.e., –P (O) (OH)2 group attached directly to the molecule via a P-C bond serve as suitable non-hydrolyzable phosphate mimics in various biomedical applications.

A polymeric phosphonate, Fyrol PMP (Figure 12) from ICL-IP, is designed for epoxy resins in printed circuit boards. The product is a solid, which melts at about 50 °C and has curing agent properties for …

Oct 27, 2016 · Additionally, the phosphonate moiety represents a source of inorganic phosphate to microorganisms that live in environments that lack this nutrient; thus, unusual enzyme reactions have …