PLIP is available as a Google Colab to be used without the need to install it locally. It can be used without constraints in terms of PDB file and protein sizes.

May 10, 2025 · PLIP detects eight types of non-covalent interactions. Initially focused on small-molecule, DNA, and RNA interactions to a protein, the current release incorporates …

Here, we present the protein–ligand interaction profiler (PLIP), a novel web service for fully automated detection and visualization of relevant non-covalent protein–ligand contacts in 3D …

PLIP latest User Guide: Introduction Installation PLIP model Run PLIP Python API C++ API Development About

Oct 27, 2025 · PLIP is available as a Google Colab to be used without the need to install it locally. It can be used without constraints in terms of PDB file and protein sizes.

May 27, 2021 · PLIP determines interactions between ligand-protein residues based on distances and/or angles, depending on the measured interaction, so it’s important that you feel …

PLIP can automatically fetch the entry from the PDB server when a valid PDB ID is provided. ```bash plip -i 1vsn -v ``` The command above will fetch the PDB entry `1vsn` from the server, …

Jul 2, 2021 · Therefore, we extended PLIP to encompass these important molecules. We demonstrate the power of this extension with examples of a cancer drug binding to a DNA …

PLIP is the first web service to provide comprehensive analysis and visualization of non-covalent protein–ligand interactions with one-click loading of structures.

Step 1 can be achieved by using the Protein-Ligand Interaction Profiler (PLIP). PLIP is an easy-to-use tool, that given a pdb file will calculate the interactions between the ligand and protein.