Semaphorins are a class of secreted and membrane proteins that were originally identified as axonal growth cone guidance molecules.

Semaphorins are extracellular signaling proteins that are essential for the development and maintenance of many organs and tissues.

Oct 12, 2018 · Semaphorins are a large family of secreted, transmembrane, or GPI-anchored proteins initially identified as axon guidance cues signaling through their receptors, neuropilins, …

Jan 15, 2025 · Semaphorins (Semas) constitute a diverse family of cell-surface signaling proteins crucial for regulating many physiological roles like embryogenesis, organ homeostasis, cell …

May 31, 2023 · The Semaphorin family is a group of proteins studied broadly for their functions in nervous systems. They consist of eight subfamilies ubiquitously expressed in vertebrates, …

May 3, 2021 · Semaphorins are a group of proteins that have been studied extensively for their critical function in neuronal development. They have been shown to regulate airway …

The semaphorins are a large family of phylogenetically conserved proteins, some of which were originally identified as repulsive axon guidance cues active during neuronal development. …

Feb 1, 2021 · Semaphorins control cancer cell behavior and hijack the function of normal cells in the tumor microenvironment. Cell-cell communication is pivotal to guide embryo development, …

Semaphorins are a diverse group of proteins that can be secreted, transmembrane, or membrane-associated. They were first discovered as regulators of nerve growth cone …

Semaphorins play fundamental roles in neural development, including axonal guidance, neuronal migration, dendritic patterning, and synaptic connectivity. They act as both repellents and …