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  1. Trajectories of fluid management after the initiation of renal ...

    This is a secondary analysis using fluid balance data focusing on individuals enrolled in the standard-strategy arm of the STARRT-AKI trial who initiated RRT. Cumulative fluid balance (CFB) following …

  2. Feb 2, 2022 · The STARRT-AKI trial was designed as a frequentist trial and was interpreted using a traditional framework of null hypothesis testing with a dichotomous interpreta-tion of p values under a …

  3. Letter to the editor regarding “Accelerated versus standard initiation ...

    Mar 9, 2021 · On the heels of the Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial [1], Pan et al. [2] recently published a systematic review …

  4. Articles | Critical Care

    Jun 3, 2025 · Critical Care, the top open access journal in critical care medicine, advances critically ill patient care with high-quality, evidence-based ...

  5. Anidulafungin compared with fluconazole therapy in critically ill ...

    Mar 1, 2010 · The 2009 IDSA Treatment Guidelines for Candidiasis favor an echinocandin for initial treatment of candidemia in patients with severe illness. In a prospective, randomized study …

  6. Correlation of cytokine levels with clinical markers of organ ...

    Mar 1, 1997 · The consequences of severe sepsis syndrome and septic shock include inadequate perfusion of organs and eventually organ failure. Organ hypoperfusion results in anaerobic glucose …

  7. Modeling the economic impact of linezolid versus vancomycin in ...

    Introduction We compared the economic impacts of linezolid and vancomycin for the treatment of hospitalized patients with methicillin-resistant Staphylococcus aureus (MRSA)–confirmed nosocomial …

  8. Oct 25, 2020 · Background: The use of indirect calorimetry (IC) is increasing due to its precision in resting energy expenditure (REE) measurement in critically ill patients. Thus, we aimed to evaluate …

  9. Putative invasive pulmonary aspergillosis in critically ill patients ...

    Introduction Patients with advanced chronic obstructive pulmonary disease (COPD) are at risk for developing invasive pulmonary aspergillosis. A clinical algorithm has been validated to discriminate …

  10. Haemodynamic optimisation: are we dynamic enough?

    Perioperative haemodynamic optimisation of high-risk surgical patients has long been documented to improve both short-term and long-term outcomes, as well as to reduce the rate of postoperative …