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  1. Epsin - Wikipedia

    Epsin is thought to have role in the angiogenesis of tumors; thus, epsin has the potential to be a target for anti-cancer therapies. Several cancers including prostate, breast, lung and skin display an …

  2. Epsins in vascular development, function and disease - PMC

    Epsins are a family of adaptor proteins involved in clathrin-dependent endocytosis. In the vasculature, epsins 1 and 2 are functionally redundant members of this family that are expressed in the …

  3. What Is the Epsin Protein and Its Role in the Body?

    Jun 17, 2025 · Epsin is a family of proteins that cells use to internalize substances from their external environment. These proteins are involved in bending the cell’s membrane to form vesicles, which are …

  4. The Epsins Define a Family of Proteins That Interact with Components …

    Epsin (epsin 1) is an interacting partner for the EH domain-containing region of Eps15 and has been implicated in conjunction with Eps15 in clathrin-mediated endocytosis. We report here the …

  5. Epsin - an overview | ScienceDirect Topics

    Epsin is defined as a protein encoded by the EPN1 gene, which consists of 551 amino acids and is located on chromosome 19q13. It is inferred to have widespread and persistent expression across …

  6. Epsins in vascular development, function and disease

    Sep 15, 2020 · Epsins are a family of adaptor proteins involved in clathrin-dependent endocytosis. In the vasculature, epsins 1 and 2 are functionally redundant members of this family that are expressed in …

  7. Epsin - Wikiwand

    Epsin is thought to have role in the angiogenesis of tumors; thus, epsin has the potential to be a target for anti-cancer therapies. Several cancers including prostate, breast, lung and skin display an …

  8. The epsin protein family: coordinators of endocytosis and signaling

    This review discusses the epsin family of endocytic proteins and their role in coordinating endocytosis and signaling. For a more detailed chronological perspective and discussion of topics, such as epsin …

  9. Epsin - Academic Dictionaries and Encyclopedias

    In the middle of the epsin sequence are two UIM's (ubiquitin -interacting motifs) located. The C-terminus contains multiple binding sites, for example for clathrin and AP2 adaptors.

  10. Epsin - an overview | ScienceDirect Topics

    Epsin is defined as a family of adaptor proteins associated with clathrin-coated pits on the cell surface, playing a significant role in the progression of atherosclerosis by influencing lipid uptake and immune …