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  1. Clinical effectiveness of fresh frozen plasma compared with fibrinogen ...

    Oct 14, 2011 · Introduction Haemostatic therapy in surgical and/or massive trauma patients typically involves transfusion of fresh frozen plasma (FFP). Purified human fibrinogen concentrate may offer …

  2. A national study of plasma use in critical care: clinical indications ...

    Apr 5, 2011 · Introduction Fresh frozen plasma (FFP) is widely used, but few studies have described patterns of plasma use in critical care. We carried out a multicentre study of coagulopathy in …

  3. Balanced massive transfusion ratios in multiple injury patients with ...

    Feb 22, 2011 · Introduction Retrospective studies have demonstrated a potential survival benefit from transfusion strategies using an early and more balanced ratio between fresh frozen plasma (FFP) …

  4. Sep 21, 2025 · Abstract Background To assess heterogeneous treatment effects of high fresh frozen plasma (FFP) to red blood cell (RBC) transfusion ratios in patients with severe blunt trauma and to …

  5. Prothrombin complex concentrate versus fresh frozen plasma in …

    Mar 21, 2006 · To reverse oral anticoagulant (OAC) therapy, a number of treatment modalities is available. Fresh frozen plasma (FFP) is effective and is currently used for coagulation factor …

  6. The effect of male-donor-only fresh frozen plasma on the incidence of ...

    Mar 22, 2007 · Transfusion-related acute lung injury, due to plasma from female donors containing antileucocyte antibodies, may be a common contributor to the development of acute lung injury (ALI) …

  7. The European guideline on management of major bleeding and …

    Mar 27, 2019 · Background Severe traumatic injury continues to present challenges to healthcare systems around the world, and post-traumatic bleeding remains a leading cause of potentially …

  8. Pre-hospital plasma transfusion: a valuable coagulation support or an ...

    Jul 1, 2019 · Moreover, the INR of FFP is 1.3 [6]. Any beneficial effect of plasma to correct slightly elevated INR is futile and plasma has primarily an effect on coagulation parameters with extended …

  9. Critical appraisal and concerns regarding a meta-analysis on ...

    Nov 21, 2023 · FFP has low doses of fibrinogen, posing challenges in maintaining fibrinogen blood concentration with plasma alone during resuscitation. Additionally, while the other studies in the meta …

  10. High-dose tranexamic acid reduces blood loss in postpartum …

    Apr 15, 2011 · In addition, TA-treated women received fewer additional procoagulant treatments, such as FFP, platelets and fibrinogen. PPH definition and blood loss measurement PPH is usually defined …